NCG is a manually curated collection of cancer genes, healthy drivers and their properties

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Accepted identifiers

  • Gene Symbol (e.g. PTEN)
  • Entrez Gene ID
  • RefSeq Protein/mRNA Identifier
  • Ensembl Protein/Gene ID

Cancer Genes

Altered genes driving cancer

591 canonical cancer drivers
  • 411 altered in coding sequence
  • 69 altered in non-coding sequence
2756 candidate cancer drivers
  • 2235 altered in coding sequence
  • 652 altered in non-coding sequence
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  • 41780 donors
  • 122 cancer types
  • 5 pan-cancer groups (17 studies)

Healthy Drivershd

Altered genes driving noncancer clones

57 canonical healthy drivers
  • 57 altered in coding sequence
  • 0 altered in non-coding sequence
38 candidate & healthy drivers
  • 38 altered in coding sequence
  • 0 altered in non-coding sequence
12 tissue types
  • 32895 donors
  • 9 healthy tissues
  • 3 diseased tissues

TIME Drivers

Cancer genes interacting with the TIME

201 canonical TIME drivers
  • 201 altered in coding sequence
  • 0 altered in non-coding sequence
395 candidate TIME drivers
  • 395 altered in coding sequence
  • 0 altered in non-coding sequence
30 cancer types
  • 6921 donors


TIME = tumour immune microenvironment

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