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Results for CD209

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CD209

Description

CD209 molecule

Aliases

CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1

Gene Identifiers

Entrez ID

30835

Ensembl Gene ID

ENSG00000090659

mRNA Identifiers

RefSeq (mRNA)

NM_001144893.2; NM_001144894.2; NM_001144895.2; NM_001144896.2; NM_001144897.2; NM_001144899.2; NM_021155.4; XM_005272472.4

Protein Identifiers

RefSeq (protein)

NP_001138365.1; NP_001138366.1; NP_001138367.1; NP_001138368.1; NP_001138369.1; NP_001138371.1; NP_066978.1; XP_005272529.1

Uniprot ID

Q9NNX6; M0R0P0; B2R907; B2R907; Q9NNX6; Q9NNX6; B2R907; B2R907; Q9NNX6; B2R907; Q9NNX6; X6RB12; B4E2A8; B2R907; B2R907; Q9NNX6

Ensembl protein ID

ENSP00000471348.1; ENSP00000204801.7; ENSP00000471137.1; ENSP00000315407.7; ENSP00000346373.5; ENSP00000377728.4; ENSP00000315477.6

Protein Architecture

SMART

domain composition

Disease Mapping

COSMIC

cancer mutations

OMIM

604672

Pubmed

Literature

Druggability

DGIdb

drugs

STITCH

compound interactions

CTD

interacting chemicals

Driver Information

Cancer gene
Damaged in 11/7921 TCGA samples
Damaged in 3/1291 cell lines

Evolutionary Conservation

Last Universal Common Ancestor

Gene Duplication

One duplicate (60% coverage)

Gene Expression in Tissues

20/30 tissues in GTEx
34/43 tissues in The Protein Atlas

Gene Expression in Cell Lines

4/1019 in CCLE
950/970 in CLP
3/675 in GenenTech

Protein Expression in Tissues

2/45 tissues in The Protein Atlas

Protein Interactions

Interacts with 20 protein(s)
Part of at least one complex

miRNA Interactions

Interacts with 54 miRNAs

Germline Variation vs. Expected

Fewer loss of function mutations
Fewer damaging SNVs/indels
Fewer structural variants

Gene Essentiality

Not essential in 1064 cell lines

Gene Function

3/6 level 1 KEGG pathways
1/26 level 1 Reactome pathways

Drug Target/Biomarker

Targeted by 0 drugs
Response/resistance in 0 cell lines
Response/resistance in 0 trials

NCG7.1

Network of Cancer Genes & Healthy Drivers