Home Query results

Results for CRTC1


Expand for information on CRTC1

CRTC1

Description
CREB regulated transcription coactivator 1
Aliases
MAML2, MECT1, Mam-2, TORC-1, TORC1, WAMTP1

Gene Identifiers

Entrez ID
23373
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
607536
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Oncogene
  • Damaged in 94/7921 TCGA samples
  • Damaged in 127/1291 cell lines

Evolutionary Conservation

  • Metazoans

Gene Duplication

  • One duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 17 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 26 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 1/1088 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials