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Results for CSF3R


Expand for information on CSF3R

CSF3R

Description
colony stimulating factor 3 receptor
Aliases
CD114, GCSFR, SCN7

Gene Identifiers

Entrez ID
1441
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
138971
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Oncogene
  • Damaged in 19/7921 TCGA samples
  • Damaged in 4/1291 cell lines

Evolutionary Conservation

  • Vertebrates

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 24 protein(s)
  • Part of at least one complex

miRNA Interactions

  • No miRNA interactions

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 1/1064 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 4 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials