Home Query results

Results for GNAS


Expand for information on GNAS

GNAS

Description
GNAS complex locus
Aliases
AHO, C20orf451, GPSA, GSA, GSP, NESP, PITA3, POH, SCG6, SgVI, GNAS

Gene Identifiers

Entrez ID
Ensembl Gene ID

Protein Architecture

Disease Mapping

COSMIC
OMIM
Pubmed

Druggability

Driver Information

  • Oncogene, healthy and TIME driver
  • Damaged in 369/7921 TCGA samples
  • Damaged in 43/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 130 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 63 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 4/1121 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 7 cell lines
  • Response/resistance in 0 trials