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Results for HMGA2


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HMGA2

Description
high mobility group AT-hook 2
Aliases
BABL, HMGI-C, HMGIC, LIPO, SRS5, STQTL9

Gene Identifiers

Entrez ID
8091
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
600698
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Oncogene
  • Damaged in 145/7921 TCGA samples
  • Damaged in 21/1291 cell lines

Evolutionary Conservation

  • Vertebrates

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 55 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 126 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1100 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials