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Results for HOXA9


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HOXA9

Description
homeobox A9
Aliases
ABD-B, HOX1, HOX1.7, HOX1G

Gene Identifiers

Entrez ID
3205
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
142956
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Cancer gene
  • Damaged in 17/7921 TCGA samples
  • Damaged in 7/1291 cell lines

Evolutionary Conservation

  • Vertebrates

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 27 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 64 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 3/1087 cell lines

Gene Function

  • 1/6 level 1 KEGG pathways
  • Not present in Reactome

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials