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Results for MAGEA6


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MAGEA6

Description
MAGE family member A6
Aliases
CT1.6, MAGE-3b, MAGE3B, MAGE6

Gene Identifiers

Entrez ID
4105
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
300176
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver, TIME driver
  • Damaged in 615/7921 TCGA samples
  • Damaged in 4/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • 6 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 111 protein(s)
  • Part of zero complexes

miRNA Interactions

  • Interacts with 20 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 11/1072 cell lines

Gene Function

  • Not present in KEGG
  • Not present in Reactome

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials