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Results for NT5C2


Expand for information on NT5C2

NT5C2

Description
5'-nucleotidase, cytosolic II
Aliases
GMP, NT5B, PNT5, SPG45, SPG65, cN-II

Gene Identifiers

Entrez ID
22978
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001134373.3; NM_001351169.2; NM_001351170.1; NM_001351171.1; NM_001351172.1; NM_001351173.1; NM_001351174.1; NM_001351175.1; NM_001351176.1; NM_001351177.1; NM_001351178.1; NM_001351179.1; NM_001351180.1; NM_001351181.1; NM_001351182.1; NM_001351183.1; NM_001351184.1; NM_001351185.1; NM_001351186.1; NM_001351187.1; NM_001351188.1; NM_001351189.1; NM_001351190.1; NM_001351191.1; NM_001351192.1; NM_001351193.1; NM_001351194.1; NM_001351195.1; NM_001351196.1; NM_001351197.1; NM_012229.4; XM_005269637.5; XM_005269645.4; XM_005269646.4; XM_006717721.3; XM_006717723.3; XM_011539537.2; XM_017015947.2; XM_017015966.1; XM_017015967.1; XM_017015974.1; XM_024447901.1; XM_024447902.1; XM_024447903.1; XM_024447904.1; XM_024447905.1; XM_024447907.1; XM_024447908.1; XM_024447909.1; XM_024447910.1; XM_024447911.1

Protein Identifiers

RefSeq (protein)
NP_001127845.1; NP_001338098.1; NP_001338099.1; NP_001338100.1; NP_001338101.1; NP_001338102.1; NP_001338103.1; NP_001338104.1; NP_001338105.1; NP_001338106.1; NP_001338107.1; NP_001338108.1; NP_001338109.1; NP_001338110.1; NP_001338111.1; NP_001338112.1; NP_001338113.1; NP_001338114.1; NP_001338115.1; NP_001338116.1; NP_001338117.1; NP_001338118.1; NP_001338119.1; NP_001338120.1; NP_001338121.1; NP_001338122.1; NP_001338123.1; NP_001338124.1; NP_001338125.1; NP_001338126.1; NP_036361.1; XP_005269694.1; XP_005269702.1; XP_005269703.1; XP_006717784.1; XP_006717786.1; XP_011537839.1; XP_016871436.1; XP_016871455.1; XP_016871456.1; XP_016871463.1; XP_024303669.1; XP_024303670.1; XP_024303671.1; XP_024303672.1; XP_024303673.1; XP_024303675.1; XP_024303676.1; XP_024303677.1; XP_024303678.1; XP_024303679.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
600417
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Oncogene
  • Damaged in 25/7921 TCGA samples
  • Damaged in 9/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 44 protein(s)
  • Part of zero complexes

miRNA Interactions

  • Interacts with 62 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 3/1062 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials