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PPARGC1B is a healthy driver


Expand for information on PPARGC1B

PPARGC1B

Description
PPARG coactivator 1 beta
Aliases
ERRL1, PERC, PGC-1(beta), PGC1B

Gene Identifiers

Entrez ID
133522
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)

Protein Identifiers

RefSeq (protein)
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
608886
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Not associated with cancer
  • Healthy driver

Evolutionary Conservation

  • Vertebrates

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 25 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 36 miRNAs

Germline Variation vs. Expected

  • No difference
  • No difference
  • No difference

Gene Essentiality

  • Essential in 149/1116 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials