Home Query results

Results for PTPRD


Expand for information on PTPRD

PTPRD

Description
protein tyrosine phosphatase receptor type D
Aliases
HPTP, HPTPD, HPTPDELTA, PTPD, R-PTP-delta, RPTPDELTA

Gene Identifiers

Entrez ID
5789
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001040712.2; NM_001171025.2; NM_001377946.1; NM_001377947.1; NM_001377958.1; NM_001378058.1; NM_002839.4; NM_130391.4; NM_130392.3; NM_130393.3; XM_006716817.4; XM_006716823.3; XM_006716825.4; XM_006716827.4; XM_006716832.4; XM_006716833.4; XM_006716834.4; XM_006716835.4; XM_006716837.4; XM_011517992.3; XM_017014958.2; XM_017014959.2; XM_017014960.2; XM_017014961.2; XM_017014963.2; XM_017014964.2; XM_017014965.2; XM_017014966.2; XM_017014967.2; XM_017014968.2; XM_017014969.2; XM_017014970.2; XM_017014971.2; XM_017014972.2; XM_017014973.2; XM_017014974.2; XM_017014975.2; XM_017014976.2; XM_017014977.2; XM_017014978.2; XM_017014979.2; XM_017014980.2; XM_017014981.2; XM_017014982.2; XM_017014983.2; XM_017014984.2; XM_017014985.2; XM_017014986.2; XM_017014987.2; XM_017014988.2; XM_017014989.2; XM_017014990.2; XM_017014991.2; XM_017014992.2; XM_017014993.2; XM_017014994.2; XM_017014995.2; XM_024447625.1; XM_024447627.1

Protein Identifiers

RefSeq (protein)
NP_001035802.1; NP_001164496.1; NP_001364875.1; NP_001364876.1; NP_001364887.1; NP_001364987.1; NP_002830.1; NP_569075.2; NP_569076.2; NP_569077.2; XP_006716880.1; XP_006716886.1; XP_006716888.1; XP_006716890.1; XP_006716895.1; XP_006716896.1; XP_006716897.1; XP_006716898.1; XP_006716900.1; XP_011516294.1; XP_016870447.1; XP_016870448.1; XP_016870449.1; XP_016870450.1; XP_016870452.1; XP_016870453.1; XP_016870454.1; XP_016870455.1; XP_016870456.1; XP_016870457.1; XP_016870458.1; XP_016870459.1; XP_016870460.1; XP_016870461.1; XP_016870462.1; XP_016870463.1; XP_016870464.1; XP_016870465.1; XP_016870466.1; XP_016870467.1; XP_016870468.1; XP_016870469.1; XP_016870470.1; XP_016870471.1; XP_016870472.1; XP_016870473.1; XP_016870474.1; XP_016870475.1; XP_016870476.1; XP_016870477.1; XP_016870478.1; XP_016870479.1; XP_016870480.1; XP_016870481.1; XP_016870482.1; XP_016870483.1; XP_016870484.1; XP_024303393.1; XP_024303395.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
601598
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Tumour suppressor, TIME driver
  • Damaged in 312/7921 TCGA samples
  • Damaged in 65/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 116 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 30 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 1/1122 cell lines

Gene Function

  • Not present in KEGG
  • 1/26 level 1 Reactome pathways

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials