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Results for RHOH

Expand for information on RHOH

RHOH

Description

ras homolog family member H

Aliases

ARHH, TTF

Gene Identifiers

Entrez ID

399

Ensembl Gene ID

ENSG00000168421

mRNA Identifiers

RefSeq (mRNA)

NM_001278359.1; NM_001278360.1; NM_001278361.1; NM_001278362.1; NM_001278363.1; NM_001278364.1; NM_001278365.2; NM_001278366.2; NM_001278367.1; NM_001278368.2; NM_001278369.1; NM_004310.5; XM_011513692.1; XM_017008188.1; XM_017008189.1; XM_024454042.1

Protein Identifiers

RefSeq (protein)

NP_001265288.1; NP_001265289.1; NP_001265290.1; NP_001265291.1; NP_001265292.1; NP_001265293.1; NP_001265294.1; NP_001265295.1; NP_001265296.1; NP_001265297.1; NP_001265298.1; NP_004301.1; XP_011511994.1; XP_016863677.1; XP_016863678.1; XP_024309810.1

Uniprot ID

Q6ICP4; Q15669; Q6ICP4; Q15669; Q6ICP4; Q15669; Q6ICP4; Q15669; Q15669; Q6ICP4; Q6ICP4; Q15669; Q15669; Q6ICP4; Q15669; Q6ICP4; Q6ICP4; Q15669; Q6ICP4; Q15669; Q15669; Q6ICP4; Q15669; Q6ICP4; Q6ICP4; Q15669; Q15669; Q6ICP4; Q6ICP4; Q15669

Ensembl protein ID

ENSP00000480192.1; ENSP00000481836.1; ENSP00000481746.1; ENSP00000480379.1; ENSP00000478248.1; ENSP00000481566.1; ENSP00000480772.1; ENSP00000425010.1; ENSP00000482947.1; ENSP00000371219.4

Protein Architecture

SMART

domain composition

Disease Mapping

COSMIC

cancer mutations

OMIM

602037

Pubmed

Literature

Druggability

DGIdb

drugs

STITCH

compound interactions

CTD

interacting chemicals

Driver Information

Tumour suppressor
Damaged in 21/7921 TCGA samples
Damaged in 10/1291 cell lines

Evolutionary Conservation

Last Universal Common Ancestor

Gene Duplication

No duplicate (60% coverage)

Gene Expression in Tissues

8/30 tissues in GTEx
36/43 tissues in The Protein Atlas

Gene Expression in Cell Lines

190/1019 in CCLE
958/970 in CLP
156/675 in GenenTech

Protein Expression in Tissues

38/45 tissues in The Protein Atlas

Protein Interactions

Interacts with 35 protein(s)
Part of at least one complex

miRNA Interactions

Interacts with 30 miRNAs

Germline Variation vs. Expected

Fewer loss of function mutations
Fewer damaging SNVs/indels
Fewer structural variants

Gene Essentiality

Essential in 1/1121 cell lines

Gene Function

2/6 level 1 KEGG pathways
1/26 level 1 Reactome pathways

Drug Target/Biomarker

Targeted by 0 drugs
Response/resistance in 0 cell lines
Response/resistance in 0 trials

NCG7.1

Network of Cancer Genes & Healthy Drivers