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Results for RIMS2


Expand for information on RIMS2

RIMS2

Description
regulating synaptic membrane exocytosis 2
Aliases
OBOE, RAB3IP3, RIM2

Gene Identifiers

Entrez ID
9699
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001100117.3; NM_001282881.2; NM_001282882.1; NM_001348484.2; NM_001348485.2; NM_001348486.2; NM_001348487.2; NM_001348488.2; NM_001348489.2; NM_001348490.2; NM_001348491.2; NM_001348492.2; NM_001348493.2; NM_001348494.2; NM_001348495.2; NM_001348496.2; NM_001348497.2; NM_001348498.2; NM_001348499.2; NM_001348500.2; NM_001348501.2; NM_001348502.2; NM_001348503.2; NM_001348504.2; NM_001348505.2; NM_001348506.2; NM_001348507.2; NM_001348508.2; NM_001348509.2; NM_014677.5; XM_005251106.3; XM_005251107.3; XM_006716698.3; XM_011517395.3; XM_011517398.3; XM_017014006.2; XM_017014007.2; XM_017014008.2; XM_017014009.2; XM_017014010.2; XM_017014011.2; XM_017014012.2; XM_017014014.1; XM_017014015.2; XM_017014016.2; XM_017014017.2; XM_017014019.2; XM_017014021.2; XM_017014022.1; XM_017014023.2; XM_017014024.2; XM_017014027.2; XM_017014028.2; XM_017014034.2; XM_017014036.1; XM_024447342.1; XM_024447343.1; XM_024447344.1; XM_024447345.1; XM_024447346.1; XM_024447347.1

Protein Identifiers

RefSeq (protein)
NP_001093587.1; NP_001269810.1; NP_001269811.1; NP_001335413.1; NP_001335414.1; NP_001335415.1; NP_001335416.1; NP_001335417.1; NP_001335418.1; NP_001335419.1; NP_001335420.1; NP_001335421.1; NP_001335422.1; NP_001335423.1; NP_001335424.1; NP_001335425.1; NP_001335426.1; NP_001335427.1; NP_001335428.1; NP_001335429.1; NP_001335430.1; NP_001335431.1; NP_001335432.1; NP_001335433.1; NP_001335434.1; NP_001335435.1; NP_001335436.1; NP_001335437.1; NP_001335438.1; NP_055492.3; XP_005251163.1; XP_005251164.1; XP_006716761.1; XP_011515697.1; XP_011515700.1; XP_016869495.1; XP_016869496.1; XP_016869497.1; XP_016869498.1; XP_016869499.1; XP_016869500.1; XP_016869501.1; XP_016869503.1; XP_016869504.1; XP_016869505.1; XP_016869506.1; XP_016869508.1; XP_016869510.1; XP_016869511.1; XP_016869512.1; XP_016869513.1; XP_016869516.1; XP_016869517.1; XP_016869523.1; XP_016869525.1; XP_024303110.1; XP_024303111.1; XP_024303112.1; XP_024303113.1; XP_024303114.1; XP_024303115.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
606630
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver, TIME driver
  • Damaged in 91/7921 TCGA samples
  • Damaged in 42/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 18 protein(s)
  • Part of zero complexes

miRNA Interactions

  • Interacts with 5 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1061 cell lines

Gene Function

  • 1/6 level 1 KEGG pathways
  • Not present in Reactome

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials