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Results for RUNX1T1


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RUNX1T1

Description
RUNX1 partner transcriptional co-repressor 1
Aliases
AML1-MTG8, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2

Gene Identifiers

Entrez ID
Ensembl Gene ID

Protein Architecture

Disease Mapping

COSMIC
OMIM
Pubmed

Druggability

Driver Information

  • Cancer gene
  • Damaged in 90/7921 TCGA samples
  • Damaged in 22/1291 cell lines

Evolutionary Conservation

  • Metazoans

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 110 protein(s)
  • Part of zero complexes

miRNA Interactions

  • Interacts with 56 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 2/1121 cell lines

Gene Function

  • 1/6 level 1 KEGG pathways
  • Not present in Reactome

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials