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Results for SETBP1

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SETBP1

Description

SET binding protein 1

Aliases

MRD29, SEB

Gene Identifiers

Entrez ID

26040

Ensembl Gene ID

ENSG00000152217

mRNA Identifiers

RefSeq (mRNA)

NM_001130110.2; NM_015559.3; XM_024451149.1; XM_024451150.1; XM_024451151.1; XM_024451152.1; XM_024451153.1; XM_024451154.1; XM_024451155.1; XM_024451156.1; XM_024451157.1; XM_024451158.1

Protein Identifiers

RefSeq (protein)

NP_001123582.1; NP_056374.2; XP_024306917.1; XP_024306918.1; XP_024306919.1; XP_024306920.1; XP_024306921.1; XP_024306922.1; XP_024306923.1; XP_024306924.1; XP_024306925.1; XP_024306926.1

Uniprot ID

Q9Y6X0; Q9Y6X0

Ensembl protein ID

ENSP00000390687.3; ENSP00000497406.1

Protein Architecture

SMART

domain composition

Disease Mapping

COSMIC

cancer mutations

OMIM

611060

Pubmed

Literature

Druggability

DGIdb

drugs

STITCH

compound interactions

CTD

interacting chemicals

Driver Information

Oncogene
Damaged in 173/7921 TCGA samples
Damaged in 44/1291 cell lines

Evolutionary Conservation

Last Universal Common Ancestor

Gene Duplication

No duplicate (60% coverage)

Gene Expression in Tissues

29/30 tissues in GTEx
39/43 tissues in The Protein Atlas

Gene Expression in Cell Lines

384/1019 in CCLE
946/970 in CLP
263/675 in GenenTech

Protein Expression in Tissues

39/45 tissues in The Protein Atlas

Protein Interactions

Interacts with 15 protein(s)
Part of zero complexes

miRNA Interactions

Interacts with 42 miRNAs

Germline Variation vs. Expected

Fewer loss of function mutations
Fewer damaging SNVs/indels
Fewer structural variants

Gene Essentiality

Essential in 1/1115 cell lines

Gene Function

Not present in KEGG
Not present in Reactome

Drug Target/Biomarker

Targeted by 0 drugs
Response/resistance in 0 cell lines
Response/resistance in 0 trials

NCG7.1

Network of Cancer Genes & Healthy Drivers