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Results for TRIP12


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TRIP12

Description
thyroid hormone receptor interactor 12
Aliases
MRD49, TRIP-12, TRIPC, ULF

Gene Identifiers

Entrez ID
9320
Ensembl Gene ID

mRNA Identifiers

RefSeq (mRNA)
NM_001284214.2; NM_001284215.2; NM_001284216.2; NM_001348315.2; NM_001348316.2; NM_001348317.1; NM_001348318.2; NM_001348319.1; NM_001348320.2; NM_001348321.1; NM_001348322.1; NM_001348323.3; NM_001348324.2; NM_001348325.2; NM_001348326.2; NM_001348327.2; NM_001348328.1; NM_001348329.2; NM_001348330.2; NM_001348331.1; NM_001348332.1; NM_001348333.1; NM_001348334.1; NM_001348335.1; NM_001348336.1; NM_004238.3; XM_005246961.4; XM_017005283.2; XM_017005289.2; XM_017005290.2; XM_024453223.1; XM_024453224.1; XM_024453225.1; XM_024453226.1; XM_024453227.1; XM_024453228.1; XM_024453229.1; XM_024453230.1; XM_024453231.1; XM_024453232.1; XM_024453233.1; XM_024453234.1; XM_024453235.1; XM_024453236.1; XM_024453237.1; XM_024453238.1; XM_024453239.1; XM_024453240.1; XM_024453241.1; XM_024453242.1; XM_024453243.1

Protein Identifiers

RefSeq (protein)
NP_001271143.1; NP_001271144.1; NP_001271145.1; NP_001335244.1; NP_001335245.1; NP_001335246.1; NP_001335247.1; NP_001335248.1; NP_001335249.1; NP_001335250.1; NP_001335251.1; NP_001335252.1; NP_001335253.1; NP_001335254.1; NP_001335255.1; NP_001335256.1; NP_001335257.1; NP_001335258.1; NP_001335259.1; NP_001335260.1; NP_001335261.1; NP_001335262.1; NP_001335263.1; NP_001335264.1; NP_001335265.1; NP_004229.1; XP_005247018.1; XP_016860772.1; XP_016860778.1; XP_016860779.1; XP_024308991.1; XP_024308992.1; XP_024308993.1; XP_024308994.1; XP_024308995.1; XP_024308996.1; XP_024308997.1; XP_024308998.1; XP_024308999.1; XP_024309000.1; XP_024309001.1; XP_024309002.1; XP_024309003.1; XP_024309004.1; XP_024309005.1; XP_024309006.1; XP_024309007.1; XP_024309008.1; XP_024309009.1; XP_024309010.1; XP_024309011.1
Uniprot ID
Ensembl protein ID

Protein Architecture

SMART
domain composition

Disease Mapping

COSMIC
cancer mutations
OMIM
604506
Pubmed
Literature

Druggability

DGIdb
drugs
STITCH
compound interactions
CTD
interacting chemicals

Driver Information

  • Candidate cancer driver, TIME driver
  • Damaged in 125/7921 TCGA samples
  • Damaged in 29/1291 cell lines

Evolutionary Conservation

  • Eukaryotes

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 126 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 9 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Equal damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Essential in 5/1081 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials